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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMPD4
All Species:
24.85
Human Site:
Y542
Identified Species:
54.67
UniProt:
Q9NXE4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE4
NP_060221.2
827
93352
Y542
L
E
G
Q
D
C
K
Y
T
P
M
F
G
P
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543560
827
93189
Y542
L
E
G
Q
D
C
K
Y
T
P
M
F
G
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPR5
823
93257
Y538
L
E
G
Q
D
C
K
Y
T
P
M
F
G
P
E
Rat
Rattus norvegicus
NP_001161278
823
93261
Y538
L
E
G
Q
D
C
K
Y
T
P
M
F
G
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509989
509
58534
E232
Y
K
Q
M
F
G
L
E
V
R
D
L
V
F
R
Chicken
Gallus gallus
XP_415236
827
94779
Y543
L
E
G
Q
D
F
Q
Y
K
Q
M
F
G
T
E
Frog
Xenopus laevis
Q5XHG1
824
93777
Y542
L
E
G
Q
D
C
Q
Y
M
Q
M
F
G
P
E
Zebra Danio
Brachydanio rerio
Q6PFJ7
791
89972
Y508
L
E
G
Q
D
C
Q
Y
N
L
M
F
G
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650124
767
86929
N487
V
S
P
G
T
P
W
N
Q
A
V
N
I
S
S
Honey Bee
Apis mellifera
XP_623882
744
86631
Q467
F
S
M
S
T
V
S
Q
Q
A
Y
L
T
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784153
874
98584
P577
H
L
L
E
V
E
A
P
G
Y
M
Y
R
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92
N.A.
89.8
90.3
N.A.
46.1
74.9
66.2
60.5
N.A.
24.2
29.5
N.A.
31
Protein Similarity:
100
N.A.
N.A.
94.5
N.A.
93.8
93.9
N.A.
51.8
83.9
77.6
71.9
N.A.
42.2
47.4
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
66.6
80
73.3
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
73.3
86.6
86.6
N.A.
13.3
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
19
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
64
0
0
0
0
0
10
0
0
0
10
% D
% Glu:
0
64
0
10
0
10
0
10
0
0
0
0
0
0
55
% E
% Phe:
10
0
0
0
10
10
0
0
0
0
0
64
0
10
0
% F
% Gly:
0
0
64
10
0
10
0
0
10
0
0
0
64
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
37
0
10
0
0
0
0
0
0
% K
% Leu:
64
10
10
0
0
0
10
0
0
10
0
19
0
0
10
% L
% Met:
0
0
10
10
0
0
0
0
10
0
73
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
10
0
37
0
0
0
64
0
% P
% Gln:
0
0
10
64
0
0
28
10
19
19
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% R
% Ser:
0
19
0
10
0
0
10
0
0
0
0
0
0
10
10
% S
% Thr:
0
0
0
0
19
0
0
0
37
0
0
0
10
10
10
% T
% Val:
10
0
0
0
10
10
0
0
10
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
64
0
10
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _